Neutralizing or mitigating the Insider Threat is a difficult task. It all comes down to the question of how we make sure that the people we entrusted with our infrastructure don’t harm the very systems they are supposed to protect. Insiders such as network engineers, system engineers, and database administrators have unfettered access to the systems that they manage. If such actors go rogue, they can use their power to inflict harm and great damage to the systems and the organization that the systems serve. In fact, the greatest threat to systems, data, and organizations, is posed by insiders. We believe that without the use of autonomous computing to make systems completely self-defending it will be truly hard to mitigate against the Insider Threat.